Pharmaceutical Theories

 

1. Drug–Receptor Theories

These explain how drugs interact with receptors.

1. Occupancy Theory
2. Rate Theory
3. Induced Fit Theory
4. Macromolecular Perturbation Theory
5. Charniere Theory
6. Two-State Receptor Theory
7. Ternary Complex Theory

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2. Medicinal Chemistry Theories

Related to drug structure and activity.

1. Lock and Key Theory
2. Pharmacophore Theory
3. QSAR (Quantitative Structure–Activity Relationship) Theory
4. Hansch Theory
5. Free-Wilson Analysis
6. Electronic Theory of Drug Action
7. Steric Theory
8. Chelation Theory

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3. Physical Pharmacy Theories

Related to physicochemical behavior of drugs.

1. Adsorption Theory
2. Diffusion Theory
3. Surface Tension Theory
4. Solubility Theory
5. Dissolution Theory
6. Partition Coefficient Theory
7. Osmotic Pressure Theory
8. Colloidal Theory

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4. Drug Release Theories

Used in controlled and sustained drug delivery systems.

1. Diffusion-Controlled Release Theory
2. Dissolution-Controlled Release Theory
3. Osmotic Pump Theory
4. Ion Exchange Theory
5. Swelling-Controlled Release Theory
6. Erosion-Controlled Release Theory

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5. Pharmacokinetic Theories

Describe movement of drugs in the body.

1. Compartment Model Theory
2. Non-Compartmental Theory
3. First-Order Kinetics
4. Zero-Order Kinetics
5. Michaelis–Menten Kinetics
6. Flip-Flop Kinetics

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6. Biopharmaceutics Theories

1. pH Partition Theory
2. Absorption Theory
3. Bioavailability Theory
4. Noyes–Whitney Dissolution Theory
5. Higuchi Model
6. Fick’s Law of Diffusion

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7. Tablet Compression & Powder Theories

1. Consolidation Theory
2. Elastic Deformation Theory
3. Plastic Deformation Theory
4. Fragmentation Theory
5. Heckel Equation Theory
6. Kawakita Theory

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8. Sterilization and Microbiology Theories

1. Thermal Death Time Theory
2. Phenol Coefficient Theory
3. Germ Theory of Disease
4. Disinfection Kinetics Theory

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9. Pharmacology Theories

1. Dose–Response Theory
2. Agonist–Antagonist Theory
3. Therapeutic Index Theory
4. Signal Transduction Theory

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10. Novel Drug Delivery Theories

1. Targeted Drug Delivery Theory
2. Nanoparticle Transport Theory
3. Liposomal Drug Delivery Theory
4. Controlled Release Theory
5. Mucoadhesion Theory

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11. Stability Theories

1. Arrhenius Theory
2. Degradation Kinetics Theory
3. Shelf-Life Prediction Theory
4. Hydrolysis and Oxidation Theory

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12. Polymer & Rheology Theories

1. Viscosity Theory
2. Newtonian Flow Theory
3. Non-Newtonian Flow Theory
4. Plastic Flow Theory
5. Thixotropy Theory